Polynucleotide (PN) treatment is a regenerative aesthetic therapy that uses highly purified DNA fragments, typically derived from salmon or trout, making them natural, biocompatible, and biodegradable.
They repair, rejuvenate, and revitalize the skin at a cellular level. It’s becoming very popular in aesthetic medicine because it promotes true skin healing and regeneration, rather than just masking aging signs.
What Polynucleotides Do
Polynucleotides work by:
• Stimulating fibroblast activity, leading to increased collagen and elastin production.
• Enhancing cell regeneration and tissue repair.
• Improving microcirculation
• Providing anti-inflammatory
Key Benefits
1. Skin Rejuvenation:
Improves skin texture, elasticity, and radiance — ideal for dull or tired skin.
2. Wrinkle Reduction:
Softens fine lines by improving dermal structure and hydration.
3. Hydration Boost:
Deeply hydrates the skin from within, unlike topical moisturizers.
4. Scar and Acne Repair:
Promotes healing and regeneration of acne scars or post-procedure wounds.
5. Redness & Sensitivity Relief:
Reduces inflammation and strengthens the skin barrier.
6. Under-Eye Rejuvenation:
Reduces dark circles, fine lines, and crepey texture under the eyes.
7. Hair Restoration:
When used on the scalp, it can improve hair thickness and stimulate regrowth by revitalizing hair follicles.
Common Treatment Areas
• Face (especially under eyes, cheeks, forehead)
• Neck and décolletage
• Hands
• Scalp
Treatment Course
• Usually done in a series of 3–4 sessions, spaced 2–4 weeks apart.
• Maintenance treatments every 6–12 months enhance long-term results.
Possible Side Effects (Minimal)
• Mild redness or swelling at injection sites (resolves within 24–48 hours)
• Slight bruising (rare)